5(6)-CR110 PEG3 alkyne
Catalog #:
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ABBFO1147-5mg | USD149.0 |
Synonyms: 5/6-Carboxyrhodamine 110-PEG3-alkyne

Functional Activity:
5(6)-CR110 PEG3 alkyne is an excellent azide-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry. The conjugate has better solubility than the parent dye carboxyrhodamine and its long PEG spacer should reduce any steric effect of the dye on the molecule to be labelled. Its excitation maximum (at 496 nm) matches the intense 488 nm spectral line of the argon ion laser commonly used in many confocal laser-scanning microscopes. Carboxyrhodamine 110 and its derivatives are, in general, signi?cantly more photostable than any other known green ?uorescent dyes including Alexa 488. In addition, the ?uorescence of the product is completely insensitive to pH between 4 and 9. Unlike Alexa 488, which is readily degraded under alkaline condition, carboxyrhodamine 110 and its derivatives are highly stable under both acidic and basic conditions. As a result, carboxyrhodamine 110 and its derivatives are superior alternatives to other green ?uorescent dyes.