U87MG cells
Catalog #:
C0005002
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| Frozen vial | USD420.0 |
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Disease:
Astrocytoma, glioblastoma
Derived from a malignant glioma from a female patient by explant technique
Homo sapiens
Brain
Epithelial
Adherent
This is a hypodiploid human cell line
Female, Caucasian, 44 yrs of age
AddexBio-formulated EMEM (C0005-01) + 10% FBS
1:2 to 1:5 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37 degree C
Complete culture medium supplemented with 5% (v/v) DMSO
I
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
AK-1, 1
ES-D, 1
G6PD, B
GLO-I, 1
Me-2, 1
PGM1, 2
PGM3, 1
Amelogenin: X
CSF1PO: 10,11
D13S317: 8,11
D7S820: 8,9
D5S818: 11,12
D16S539: 12
vWA: 15,17
THO1: 9.3
TPOX: 8
If use of this culture results in a scientific publication, it should be cited in the publication as: U87MG (AddexBio C0005002)
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References for U87MG cells:
1. Deng, J. Y., Chen, S. J., Jow, G. M., Hsueh, C. W., and Jeng, C. J. Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas. Chem Res Toxicol, 22: 1817-1826, 2009.
2. Diaz Miqueli, A., Rolff, J., Lemm, M., Fichtner, I., Perez, R., and Montero, E. Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies. Br J Cancer, 100: 950-958, 2009.
3. Frankel, P., Pellet-Many, C., Lehtolainen, P., D'Abaco, G. M., Tickner, M. L., Cheng, L., and Zachary, I. C. Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway. EMBO Rep, 9: 983-989, 2008.
4. Karmakar, S., Banik, N. L., and Ray, S. K. Curcumin suppressed anti-apoptotic signals and activated cysteine proteases for apoptosis in human malignant glioblastoma U87MG cells. Neurochem Res, 32: 2103-2113, 2007.
5. Karmakar, S., Banik, N. L., and Ray, S. K. Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice. Cancer, 112: 596-607, 2008.
6. Martinkova, E., Dontenwill, M., Frei, E., and Stiborova, M. Cytotoxicity of and DNA adduct formation by ellipticine in human U87MG glioblastoma cancer cells. Neuro Endocrinol Lett, 30 Suppl 1: 60-66, 2009.
7. Zhang, R., Banik, N. L., and Ray, S. K. Combination of all-trans retinoic acid and interferon-gamma upregulated p27(kip1) and down regulated CDK2 to cause cell cycle arrest leading to differentiation and apoptosis in human glioblastoma LN18 (PTEN-proficient) and U87MG (PTEN-deficient) cells. Cancer Chemother Pharmacol, 62: 407-416, 2008.
