K1 cells
Catalog #:
C0025003
Use only Express Delivery (overnight) for cell lines. International shipping rate please contact us for detailsShipping advice:
| Frozen vial | USD520.0 |
Disease:
Thyroid carcinoma
Derived from a primary papillary thyroid carcinoma, but retains thyroid follicular cell differentiation
Homo sapiens
Thyroid gland
Epithelial
Adherent
Tumorigenic
RPMI1640 + 10% FBS, 1x MEM non-essential AA
1:2 to 1:4 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
Origin:
Species:
Tissue:
Morphology:
Properties:
Cytogenic data:
Patient:
Medium:
Subculture:
Freezing Medium:
Biosafety Level:
I
Sterility:
Pathogens:
Protein Expression:
Wild-type p53 tumour suppressor gene
Related cells by Organ:
References for K1 cells:
1. Yuan, G. B., Kuang, A. R., Fan, Q., Yu, L. B., and Mi, Y. X. Combined effects of all-trans-retinoic acid and trichostatin A on the induction of differentiation of thyroid carcinoma cells K1. Chin J Cancer, 29: 379-384.
2. Liu, D., Hou, P., Liu, Z., Wu, G., and Xing, M. Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer K1 cells to therapeutic targeting of Akt and mammalian target of rapamycin. Cancer Res, 69: 7311-7319, 2009.
3. Hibma, M. H., Real, N. C., Wiles, A., Dobson-Le, D., Dix, B. R., Wynford-Thomas, D., Braithwaite, A. W., and Royds, J. A. Increased apoptosis and reduced replication efficiency of the E3 region-modified dl309 adenovirus in K1 cancer cells. Virus Res, 145: 112-120, 2009.
4. Schweppe, R. E., Kerege, A. A., Sharma, V., Poczobutt, J. M., Gutierrez-Hartmann, A., Grzywa, R. L., and Haugen, B. R. Distinct genetic alterations in the mitogen-activated protein kinase pathway dictate sensitivity of thyroid K1 cancer cells to mitogen-activated protein kinase kinase 1/2 inhibition. Thyroid, 19: 825-835, 2009.
5. Desailloud, R., Sane, F., Caloone, D., and Hober, D. Persistent infection of a carcinoma thyroid K1 cell line with coxsackievirus B. Thyroid, 19: 369-374, 2009.
6. Lavra, L., Ulivieri, A., Rinaldo, C., Dominici, R., Volante, M., Luciani, E., Bartolazzi, A., Frasca, F., Soddu, S., and Sciacchitano, S. Gal-3 is stimulated by gain-of-function p53 mutations and modulates chemoresistance in anaplastic K1 thyroid carcinomas. J Pathol, 218: 66-75, 2009.
