Botulinum Neurotoxin (BoNT) B Substrate Modification, amide, FITC - labeled

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Synonyms: FITC-LC-LSELDDRADALQAGASQFESSAAKLKRKYWWKNLK-NH2

Functional Activity:

This is a fluorescent (FITC)-labeled botulinum neurotoxin peptide with a BoNT B [Leu 97 (64-98)] substrate peptide modification at Abs/Em=494/520 nm. This peptide is also a modified fragment of the synapatic vesicle-associated membrane protein 1, a nervous-system-specific protein of 120 amino acids.

Technical Data:

M.Wt: 4516

Sequence (one-letter code): FITC-LC-LSELDDRADALQAGASQFESSAAKLKRKYWWKNLK-NH2

Sequence (three-letter code): FITC - LC - Leu - Ser - Glu - Leu - Asp - Asp - Arg - Ala - Asp - Ala - Leu - Gln - Ala - Gly - Ala - Ser - Gln - Phe - Glu - Ser - Ser - Ala - Ala - Lys - Leu - Lys - Arg - Lys - Tyr - Trp - Trp - Lys - Asn - Leu - Lys - NH2

Excitation (nm): 492

Emission (nm): 516

Solubility: Soluble in DMSO

Purity: >95% (HPLC)

Shipping Conditions: Room temperature

Storage: Store and desiccate at -20°C and protect from light.

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References for Botulinum Neurotoxin (BoNT) B Substrate Modification, amide, FITC - labeled :

1. Trimble, WS. et al. Proc. Natl. Acad. Sci. USA 85, 4538 (1988),

2. Barr, J. et al. Emerg. Inf. Dis. 11, 1578 (2005).

3. Dong, M. et al. J. Cell Biol. 162, 1293 (2003).

Certificate of Analysis/MSDS is available upon request

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