5 - TMR - RRKDLHDDEEDEAMSITA (a CKI substrate)

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Synonyms: RRKDLHDDEEDEAMSITA, 5 - TMR LABELED

Functional Activity:

The native peptide, RRKDLHDDEEDEAMSITA, is a substrate for casein kinase I. Its turnover rate is higher than that of casein. Its Km is 172 μM and the Vmax is 6-fold higher than that of casein. Phosphorylation rate of this substrate by casein kinase II is negligible.

Technical Data:

M.Wt: 2543.7

Sequence (one-letter code): 5 - TMR - RRKDLHDDEEDEAMSITA

Sequence (three-letter code): 5 - TMR - Arg - Arg - Lys - Asp - Leu - His - Asp - Asp - Glu - Glu - Asp - Glu - Ala - Met - Ser - Ile - Thr - Ala - OH

Excitation (nm): 547

Emission (nm): 573

Solubility: Soluble in DMSO

Purity: >95% (HPLC)

Shipping Conditions: Room temperature

Storage: Store and desiccate at -20°C and protect from light.

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References for 5 - TMR - RRKDLHDDEEDEAMSITA :

1. Marin O. et al. Biochem. Biophys. Res. Commun. 198, 898 (1994).

2. Pinna LA. Cell. Mol. Biol. Res. 40, 38390 (1994).

Certificate of Analysis/MSDS is available upon request

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