Caco-2 cells
Catalog #:
C0009009
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Disease:
Colonic adenocarcinoma
Homo sapiens
Colon
Epithelial
Adherent
Hypertetraploid
Male, Caucasian, 72 yrs of age
AddexBio-formulated EMEM (C0005-01) + 20% FBS
1:4 to 1:6 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
I
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Resistant
Hepatitis B: Negative
Hepatitis C: Negative
Amelogenin: X , X
CSF1PO: 11
D13S317: 11, 13, 14
D16S539: 12, 13
D5S818: 12, 13
D7S820: 12
THO1: 6
TPOX: 9, 11
vWA: 16, 18
If use of this culture results in a scientific publication, it should be cited in the publication as: Caco-2 (AddexBio C0009009)
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Protein Expression:
heat stable enterotoxin (Sta, E. coli); epidermal growth factor (EGF)
Isoenzymes:
Me-2, 1; PGM3, 1; PGM1, 1; ES-D, 1; AK-1, 1; GLO-1, 1; G6PD, B
DNA Profile (STR):
Citation Format:
Related cells by Organ:
References for Caco-2 cells:
1. Chen, H., Attieh, Z. K., Dang, T., Huang, G., van der Hee, R. M., and Vulpe, C. Decreased hephaestin expression and activity leads to decreased iron efflux from differentiated Caco2 cells. J Cell Biochem, 107: 803-808, 2009.
2. Cosentino, S., Gravaghi, C., Donetti, E., Donida, B. M., Lombardi, G., Bedoni, M., Fiorilli, A., Tettamanti, G., and Ferraretto, A. Caseinphosphopeptide-induced calcium uptake in human intestinal cell lines HT-29 and Caco2 is correlated to cellular differentiation. J Nutr Biochem, 21: 247-254.
3. Mangian, H. F. and Tappenden, K. A. Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. JPEN J Parenter Enteral Nutr, 33: 607-617; discussion 617, 2009.
4. Petruzzelli, M., Groen, A. K., van Erpecum, K. J., Vrins, C., van der Velde, A. E., Portincasa, P., Palasciano, G., van Berge Henegouwen, G. P., Lo Sasso, G., Morgano, A., and Moschetta, A. Micellar lipid composition profoundly affects LXR-dependent cholesterol transport across CaCo2 cells. FEBS Lett, 583: 1274-1280, 2009.
5. Savini, I., Arnone, R., Catani, M. V., and Avigliano, L. Origanum vulgare induces apoptosis in human colon cancer caco2 cells. Nutr Cancer, 61: 381-389, 2009.
6. Sun, X., Ge, R., Cai, Z., Sun, H., and He, Q. Y. Iron depletion decreases proliferation and induces apoptosis in a human colonic adenocarcinoma cell line, Caco2. J Inorg Biochem, 103: 1074-1081, 2009.