BxPc-3 cells
Catalog #:
C0018003
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| Frozen vial | USD420.0 |
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Disease:
Primary Pancreatic adenocarcinoma
BxPC-3 cells produce mucin and the tumour produced in a nude mouse is moderately well to poorly differentiated like the primary adenocarcinoma
Homo sapiens
Pancreas
Epithelial
Adherent
Tumorigenic; 2n = 59, near triploid
Female, 61 yrs of age
AddexBio-formulated RPMI-1640 Medium(C0004-01) + 10% FBS
1:3 to 1:6 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
Origin:
Species:
Tissue:
Morphology:
Properties:
Cytogenic data:
Patient:
Medium:
Subculture:
Freezing Medium:
Biosafety Level:
I
Sterility:
Pathogens:
Protein Expression:
mucin
DNA Profile (STR):
Amelogenin: X;
CSF1PO: 13;
D13S317: 11;
D16S539: 9,11;
D5S818: 11;
D7S820: 10,13;
THO1: 9;
TPOX: 8;
vWA: 14,18
Related cells by Organ:
References for BxPc-3 cells:
1. Bernhaus, A., Ozsvar-Kozma, M., Saiko, P., Jaschke, M., Lackner, A., Grusch, M., Horvath, Z., Madlener, S., Krupitza, G., Handler, N., Erker, T., Jaeger, W., Fritzer-Szekeres, M., and Szekeres, T. Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells. Invest New Drugs, 27: 393-401, 2009.
2. Lu, Y. Y., Jing, D. D., Xu, M., Wu, K., and Wang, X. P. Anti-tumor activity of erlotinib in the BxPC-3 pancreatic cancer cell line. World J Gastroenterol, 14: 5403-5411, 2008.
3. Nyaga, S. G., Lohani, A., and Evans, M. K. Deficient repair of 8-hydroxyguanine in the BxPC-3 pancreatic cancer cell line. Biochem Biophys Res Commun, 376: 336-340, 2008.
4. Yeo, T. K., Kintner, J., Armand, R., Perez, R., and Lewis, L. D. Sublethal concentrations of gemcitabine (2',2'-difluorodeoxycytidine) alter mitochondrial ultrastructure and function without reducing mitochondrial DNA content in BxPC-3 human pancreatic carcinoma cells. Hum Exp Toxicol, 26: 911-921, 2007.
5. Huang, Z., Guo, K. J., Guo, R. X., and He, S. G. Effects of 5-fluouracil combined with sulfasalazine on human pancreatic carcinoma cell line BxPC-3 proliferation and apoptosis in vitro. Hepatobiliary Pancreat Dis Int, 6: 312-320, 2007.
6. Ahsan, H., Reagan-Shaw, S., Breur, J., and Ahmad, N. Sanguinarine induces apoptosis of human pancreatic carcinoma AsPC-1 and BxPC-3 cells via modulations in Bcl-2 family proteins. Cancer Lett, 249: 198-208, 2007.
