KATO III cells
Catalog #:
C0023001
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Disease:
Gastric carcinoma
Derived from metastatic pleural effusion; supraclavicular and axillary lymph nodes and Douglas cul-de-sac
Homo sapiens
Stomach
Sperical
Mixed Suspension and Adherent for long term culture
Tumorigenic; The stemline chromosome number is hypotetraploid
Male, Asian, 55 yrs of age
IMDM + 20% FBS
1:2 to 1:8 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
Origin:
Species:
Tissue:
Morphology:
Properties:
Cytogenic data:
Patient:
Medium:
Subculture:
Freezing Medium:
Biosafety Level:
I
Sterility:
Pathogens:
Protein Expression:
Isoenzymes:
AK-1, 1;
ES-D, 1;
G6PD, B;
GLO-I, 2;
PGM1, 1;
PGM3, 1;
DNA Profile (STR):
Amelogenin: X;
CSF1PO: 7,11;
D13S317: 8,12;
D16S539: 10,12;
D5S818: 10,11;
D7S820: 8,12;
THO1: 7,9;
TPOX: 11;
vWA: 14,16
References for KATO III cells:
1. Hofbauer, R., Pasching, E., Moser, D., and Frass, M. Heparin-binding epidermal growth factor expression in KATO-III cells after Helicobacter pylori stimulation under the influence of strychnos Nux vomica and Calendula officinalis. Homeopathy, 99: 177-182.
2. Itoh, H., Ito, H., and Hibasami, H. Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells. Oncol Rep, 20: 1359-1361, 2008.
3. Pazos, Y., Alvarez, C. J., Camina, J. P., and Casanueva, F. F. Stimulation of extracellular signal-regulated kinases and proliferation in the human gastric cancer cells KATO-III by obestatin. Growth Factors, 25: 373-381, 2007.
4. Hibasami, H., Takagi, K., Ishii, T., Tsujikawa, M., Imai, N., and Honda, I. Induction of apoptosis by rhapontin having stilbene moiety, a component of rhubarb (Rheum officinale Baillon) in human stomach cancer KATO III cells. Oncol Rep, 18: 347-351, 2007.
5. Matthews, G. M., Howarth, G. S., and Butler, R. N. Short-chain fatty acid modulation of apoptosis in the Kato III human gastric carcinoma cell line. Cancer Biol Ther, 6: 1051-1057, 2007.
6. Kasuga, T., Tabuchi, T., Shirato, K., Imaizumi, K., and Tomoda, A. Caspase-independent cell death revealed in human gastric cancer cell lines, MKN45 and KATO III treated with phenoxazine derivatives. Oncol Rep, 17: 409-415, 2007.