FTC-238 cells
Catalog #:
C0025001
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Frozen vial | USD520.0 |
Disease:
Follicular thyroid carcinoma
Established from a lung metastasis of a follicular thyroid carcinoma
Homo sapiens
Thyroid gland
Polymorphic
Adherent
Tumorigenic; complex chromosomal changes were detected as well as a p53 mutation
Male, 42 yrs of age
DMEM/F12 + 5% FBS
1:10 to 1:20 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C
Complete culture medium supplemented with 5% (v/v) DMSO
Bacteria: Negative
Yeast: Negative
Mycoplasma: Negative
HIV: Negative
Hepatitis B: Negative
Hepatitis C: Negative
Origin:
Species:
Tissue:
Morphology:
Properties:
Cytogenic data:
Patient:
Medium:
Subculture:
Freezing Medium:
Biosafety Level:
I
Sterility:
Pathogens:
Protein Expression:
5' - Deiodinase Type I, p53 mutated
Related cells by Organ:
References for FTC-238 cells:
1. Song, M., Kim, Y. J., Song, M. K., Choi, H. S., Park, Y., and Ryu, J. C. Identification of Classifiers for Increase or Decrease of Thyroid Peroxidase Activity in the FTC-238/hrTPO Recombinant Cell Line. Environ Sci Technol.
2. Mitmaker, E. J., Griff, N. J., Grogan, R. H., Sarkar, R., Kebebew, E., Duh, Q. Y., Clark, O. H., and Shen, W. T. Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines FTC-238 using demethylating agents and histone deacetylase inhibitors. Surgery, 149: 504-511.
3. Trojanowicz, B., Sekulla, C., Lorenz, K., Kohrle, J., Finke, R., Dralle, H., and Hoang-Vu, C. Proteomic approach reveals novel targets for retinoic acid-mediated therapy of thyroid carcinoma FTC-238. Mol Cell Endocrinol, 325: 110-117.
4. Stepulak, A., Luksch, H., Gebhardt, C., Uckermann, O., Marzahn, J., Sifringer, M., Rzeski, W., Staufner, C., Brocke, K. S., Turski, L., and Ikonomidou, C. Expression of glutamate receptor subunits in human cancers FTC-238. Histochem Cell Biol, 132: 435-445, 2009.
5. Trojanowicz, B., Winkler, A., Hammje, K., Chen, Z., Sekulla, C., Glanz, D., Schmutzler, C., Mentrup, B., Hombach-Klonisch, S., Klonisch, T., Finke, R., Kohrle, J., Dralle, H., and Hoang-Vu, C. Retinoic acid-mediated down-regulation of ENO1/MBP-1 gene products caused decreased invasiveness of the follicular thyroid carcinoma cell lines FTC-238. J Mol Endocrinol, 42: 249-260, 2009.
6. Seifert, A., Klonisch, T., Wulfaenger, J., Haag, F., Dralle, H., Langner, J., Hoang-Vu, C., and Kehlen, A. The cellular localization of autotaxin impacts on its biological functions in human thyroid carcinoma cells FTC-238. Oncol Rep, 19: 1485-1491, 2008.