CDK5 Substrate [PKTPKKAKKL], 5 - FAM labeled

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Synonyms: 5-FAM-PKTPKKAKKL

Functional Activity:

The native peptide PKTPKKAKKL is derived from histone H1 peptide sequence that is docked in the active site of cyclin-dependent kinase 5. It is an effective CDK5 substrate (Km = 40 μM).

Technical Data:

M.Wt: 1496.8

Sequence (one-letter code): 5-FAM-PKTPKKAKKL

Sequence (three-letter code): 5 - FAM - Pro - Lys - Thr - Pro - Lys - Lys - Ala - Lys - Lys - Leu - OH

Excitation (nm): 494

Emission (nm): 521

Solubility: Soluble in DMSO

Purity: >95% (HPLC)

Shipping Conditions: Room temperature

Storage: Store and desiccate at -20°C and protect from light.

Related Products by Target:

References for CDK5 Substrate [PKTPKKAKKL], 5 - FAM labeled :

1. Lew, J. Biochem. 42, 849 (2003)

2. Sharma, P. et al. J. Biol. Chem. 274, 9600 (1999).

3. Dong, M. et al. J. Cell Biol. 162, 1293 (2003).

Certificate of Analysis/MSDS is available upon request

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