5 - TAMRA cadaverine

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Synonyms: Tetramethylrhodamine - 5 - carboxamide cadaverine

Functional Activity:

5-TAMRA cadaverine is the purified single isomer of 5(6)-TAMRA cadaverine mixture. It is often used as a building block for developing fluoresceinated bioconjugates. It is also a fluorescent transglutaminase substrate to label proteins by transaminidation. It is preferred for some complicated biological applications where reproducibility is critical since the minor positional difference between 5-isomer and 6-isomer might have biological implications. TAMRA (TMR) is one of the most popular fluorophores used in various bioconjugations. TAMRAis a bright orange fluorophore.

Technical Data:

M.Wt: 514.62

Formula: C₃₀H₃₆N₄O₄

Excitation (nm): 545

Emission (nm): 576

Solubility: Soluble in DMSO, DMF

Purity: >95% (HPLC)

Shipping Conditions: Room temperature

Storage: Store and desiccated at -20°C and protect from light.

CAS No.: N/A

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References for 5 - TAMRA cadaverine :

1. Nagatoishi S, Nojima T, Galezowska E, Juskowiak B, Takenaka S. (2006) G Quadruplex- Based FRET Probes with the Thrombin-Binding Aptamer (TBA) Sequence Designed for the Efficient Fluorometric Detection of the Potassium Ion. Chembiochem, 7, 1730.

2. Fischer R, Bachle D, Fotin-Mleczek M, Jung G, Kalbacher H, Brock R. (2006) A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway. Chembiochem, 7, 1428.