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L-Canavanine sulfate

Catalog #:

IN0107-10mg USD29.0

References for L-Canavanine sulfate:

1. Vynnytska-Myronovska, B., Bobak, Y., Garbe, Y., Dittfeld, C., Stasyk, O., and Kunz-Schughart, L. A. Single amino acid arginine starvation efficiently sensitizes cancer cells to canavanine treatment and irradiation. Int J Cancer.

2. Vynnytska, B. O., Mayevska, O. M., Kurlishchuk, Y. V., Bobak, Y. P., and Stasyk, O. V. Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells. Anticancer Drugs, 22: 148-157.

3. Bence, A. K. and Crooks, P. A. The mechanism of L-canavanine cytotoxicity: arginyl tRNA synthetase as a novel target for anticancer drug discovery. J Enzyme Inhib Med Chem, 18: 383-394, 2003.

4. Bence, A. K., Adams, V. R., and Crooks, P. A. L-Canavanine as a radiosensitization agent for human pancreatic cancer cells. Mol Cell Biochem, 244: 37-43, 2003.

5. Miersch, J., Grancharov, K., Pajpanova, T., Tabakova, S., Stoev, S., Krauss, G. J., and Golovinsky, E. Synthesis and biological activity of canavanine hydrazide derivatives. Amino Acids, 18: 41-59, 2000.

6. Yang, W., Urano, J., and Tamanoi, F. Protein farnesylation is critical for maintaining normal cell morphology and canavanine resistance in Schizosaccharomyces pombe. J Biol Chem, 275: 429-438, 2000.

Certificate of Analysis/MSDS is available upon request with lot number

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