Capsaicin

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Synonyms: (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide, CPS

IUPAC Name:

(E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide

Functional Activity:

Selective TRPV channel activator (pEC50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively).

Technical Data:

M.Wt: 305.42

Formula: C₁₈H₂₇ NO₃

Solubility: Soluble to 50 mM in DMSO and to 50 mM in ethanol

Purity: >99%

Storage: Dessicate at RT

CAS No.: 404-86-4

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References for Capsaicin:

1. Bevan et al., Sensory neuron-specific actions of capsaicin: mechanisms and application. TiPS 11:330, 1990.

2. Holzer: Capsaicin-cellular targets, mechanism of actions, and selectivity for thin sensory neurons. Pharmacol. Rev. 43:143, 1991.

Certificate of Analysis/MSDS is available upon request with lot number