5-(N,N-Dimethyl)amiloride hydrochloride

Catalog #:

IN0083

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IN0083-25mg

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Synonyms: 5-(N,N-Dimethyl)amiloride hydrochloride, 3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride, 3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride, DMA, 5-(N,N-dimethyl)-Amiloride,

IUPAC Name:

3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2- carboxamide hydrochloride

Functional Activity:

Selective inhibitor of Na⁺/H⁺ antiport (IC50 = 6.9 μM)

Technical Data:

M.Wt: 294.14

Formula: C₈H₁₂ ClN₇O.HCl

Solubility: Soluble in DMSO

Purity: >98%

Storage: Dessicate at 4°C

CAS No.: 1214-79-5

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References for 5-(N,N-Dimethyl)amiloride hydrochloride:

1. Chang, C., Kong, P. Y., Chen, X. H., Peng, X. G., Liu, L., Liu, H., Zeng, D. F., Liang, X., and Wang, Q. Y. [Effect of the NHE-1-specific inhibitor DMA on pHi, proliferation and apoptosis of HL-60/ADM cells in vitro]. Zhongguo Shi Yan Xue Ye Xue Za Zhi, 14: 488-491, 2006.

Certificate of Analysis/MSDS is available upon request with lot number