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Cyclopiazonic acid, CPA

Catalog #:

IN0068-5mg USD52.0

References for Cyclopiazonic acid (CPA) :

1. Liu, X. and Walsh, C. T. Characterization of cyclo-acetoacetyl-L-tryptophan dimethylallyltransferase in cyclopiazonic acid biosynthesis: substrate promiscuity and site directed mutagenesis studies. Biochemistry, 48: 11032-11044, 2009.

2. Liu, X. and Walsh, C. T. Cyclopiazonic acid biosynthesis in Aspergillus sp.: characterization of a reductase-like R* domain in cyclopiazonate synthetase that forms and releases cyclo-acetoacetyl-L-tryptophan. Biochemistry, 48: 8746-8757, 2009.

3. Seshime, Y., Juvvadi, P. R., Tokuoka, M., Koyama, Y., Kitamoto, K., Ebizuka, Y., and Fujii, I. Functional expression of the Aspergillus flavus PKS-NRPS hybrid CpaA involved in the biosynthesis of cyclopiazonic acid. Bioorg Med Chem Lett, 19: 3288-3292, 2009.

4. Moldes-Anaya, A. S., Asp, T. N., Eriksen, G. S., Skaar, I., and Rundberget, T. Determination of cyclopiazonic acid in food and feeds by liquid chromatography-tandem mass spectrometry. J Chromatogr A, 1216: 3812-3818, 2009.

5. Zhang, W. B. and Kwan, C. Y. Unrepeatable extracellular Ca2+-dependent contractile effects of cyclopiazonic acid in rat vascular smooth muscle. Eur J Pharmacol, 610: 81-86, 2009.

6. Laursen, M., Bublitz, M., Moncoq, K., Olesen, C., Moller, J. V., Young, H. S., Nissen, P., and Morth, J. P. Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase. J Biol Chem, 284: 13513-13518, 2009.

Certificate of Analysis/MSDS is available upon request with lot number

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