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Catalog #:

IN0046-50mg USD39.0

References for Terfenadine:

1. Chen, C., Li, G., Liao, W., Wu, J., Liu, L., Ma, D., Zhou, J., Elbekai, R. H., Edin, M. L., Zeldin, D. C., and Wang, D. W. Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther, 329: 908-918, 2009.

2. Jangi, S. M., Ruiz-Larrea, M. B., Nicolau-Galmes, F., Andollo, N., Arroyo-Berdugo, Y., Ortega-Martinez, I., Diaz-Perez, J. L., and Boyano, M. D. Terfenadine-induced apoptosis in human melanoma cells is mediated through Ca2+ homeostasis modulation and tyrosine kinase activity, independently of H1 histamine receptors. Carcinogenesis, 29: 500-509, 2008.

3. Liu, J. D., Wang, Y. J., Chen, C. H., Yu, C. F., Chen, L. C., Lin, J. K., Liang, Y. C., Lin, S. Y., and Ho, Y. S. Molecular mechanisms of G0/G1 cell-cycle arrest and apoptosis induced by terfenadine in human cancer cells. Mol Carcinog, 37: 39-50, 2003.

4. Wang, Y. J., Yu, C. F., Chen, L. C., Chen, C. H., Lin, J. K., Liang, Y. C., Lin, C. H., Lin, S. Y., Chen, C. F., and Ho, Y. S. Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity. J Cell Biochem, 87: 147-159, 2002.

5. Munakata, Y., Umezawa, Y., Iwata, S., Dong, R. P., Yoshida, S., Ishii, T., and Morimoto, C. Specific inhibition of TH2-type cytokine production from human peripheral T cells by terfenadine in vitro. Clin Exp Allergy, 29: 1281-1286, 1999.

6. Kamisako, T., Adachi, Y., Nakagawa, H., and Yamamoto, T. Torsades de pointes associated with terfenadine in a case of liver cirrhosis and hepatocellular carcinoma. Intern Med, 34: 92-95, 1995.

7. Campbell, A. M., Chanez, P., Marty-Ane, C., Albat, B., Bloom, M., Michel, F. B., Godard, P., and Bousquet, J. Modulation of eicosanoid and histamine release from human dispersed lung cells by terfenadine. Allergy, 48: 125-129, 1993.

8. Hait, W. N., Gesmonde, J. F., Murren, J. R., Yang, J. M., Chen, H. X., and Reiss, M. Terfenadine (Seldane): a new drug for restoring sensitivity to multidrug resistant cancer cells. Biochem Pharmacol, 45: 401-406, 1993.

Certificate of Analysis/MSDS is available upon request with lot number

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