Azidohomoanaline (AHA)

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Synonyms: AHA, 2(S)-Amino-4-azido-butanoic Acid

IUPAC Name:

(S)-2-amino-4-azidobutanoic acid

Functional Activity:

It is is a novel mutagenic amino acid. Used for decoration of E.coli proteins with azide residues modified via Staudinger-Bertozzi ligations. A probe useful for selective identification of newly synthesized proteins in mammalian cells using the technology of bioorthogonal noncanonical amino acid tagging (BONCAT).

Technical Data:

M.Wt: 144.13

Formula: C₄H₈N₄O₂

Solubility: Soluble in water

Purity: >95% (LCMS)

Storage: -20°C

CAS No.: 120042-14-0

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References for Azidohomoanaline :

1. K. L. Kiick, E. Saxon, D. A. Tirell and C. R. Bertozzi, Proc. Natl. Acad. Sci. USA, 2002, 99, 19-24.

2.Dieterich, D.C. et al. Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging. Nat. Protoc. 2007, 2, 532-540.

Certificate of Analysis/MSDS is available upon request with lot number