Synonyms: 4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamide hydrate, 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide hydrate, 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]-benzamide hydrate

IUPAC Name:

4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide

Functional Activity:

Potent and selective inhibitor of transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase (ALK) receptors. It suppresses TGFβ-induced proliferation of osteosarcoma cells, but stimulates proliferation, differentiation and sheet formation of endothelial cells.

Technical Data:

M.Wt: 384.39 (anhydrous basis)

Formula: C₂₂H₁₆N₄O₃.xH₂O

Solubility: Soluble in DMSO

Purity: >98%

Storage: Dessicate at -20°C

CAS No.: 301836-41-9

Related Products by Target:

References for SB 431542

Certificate of Analysis/MSDS is available upon request with lot number