5-TAMRA, SE

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Synonyms: 5 - Carboxytetramethylrhodamine, succinimidyl ester

Functional Activity:

5-TAMRA, SE is the single isomer of the amine reactive carboxytetramethylrhodamine (TAMRA) succinimidyl ester. 5-TAMRA, SE is predominantly used for labeling peptides and proteins while 6-TAMRA, SE is often used for labeling nucleotides and sequencing nucleic acids. The single TAMRA isomers are increasingly preferred for labeling peptides and nucleotides because they give better resolution in HPLC purification that is often required in the conjugation processes.

Technical Data:

M.Wt: 527.53

Formula: C₂₉H₂₅N₃O₇

Excitation (nm): 547

Emission (nm): 574

Solubility: Soluble in DMSO, DMF

Purity: >95% (HPLC)

Shipping Conditions: Room temperature

Storage: Store and desiccated at -20°C and protect from light.

CAS No.: 150810-68-7

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References for 5-TAMRA, SE :

1. Nagatoishi S, Nojima T, Galezowska E, Juskowiak B, Takenaka S. (2006) G Quadruplex- Based FRET Probes with the Thrombin-Binding Aptamer (TBA) Sequence Designed for the Efficient Fluorometric Detection of the Potassium Ion. Chembiochem, 7, 1730.

2. Fischer R, Bachle D, Fotin-Mleczek M, Jung G, Kalbacher H, Brock R. (2006) A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway. Chembiochem, 7, 1428.