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AG 490

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IN0123-5mg USD49.0

References for AG 490

1. Seo, I. A., Lee, H. K., Shin, Y. K., Lee, S. H., Seo, S. Y., Park, J. W., and Park, H. T. Janus Kinase 2 Inhibitor AG490 Inhibits the STAT3 Signaling Pathway by Suppressing Protein Translation of gp130. Korean J Physiol Pharmacol, 13: 131-138, 2009.

2. Wu, M. H., Chen, X. Y., and Cai, K. R. Effects of a JAK inhibitor, AG490, on proliferation and apoptosis of human nasopharyngeal carcinoma cell line CNE-2Z. Ai Zheng, 28: 24-28, 2009.

3. Tsuchiya, Y., Takahashi, N., Yoshizaki, T., Tanno, S., Ohhira, M., Motomura, W., Tanno, S., Takakusaki, K., Kohgo, Y., and Okumura, T. A Jak2 inhibitor, AG490, reverses lipin-1 suppression by TNF-alpha in 3T3-L1 adipocytes. Biochem Biophys Res Commun, 382: 348-352, 2009.

4. Caceres-Cortes, J. R. A potent anti-carcinoma and anti-acute myeloblastic leukemia agent, AG490. Anticancer Agents Med Chem, 8: 717-722, 2008.

5. Kwak, H. B., Sun, H. M., Ha, H., Lee, J. H., Kim, H. N., and Lee, Z. H. AG490, a Jak2-specific inhibitor, induces osteoclast survival by activating the Akt and ERK signaling pathways. Mol Cells, 26: 436-442, 2008.

6. Chen, H. F., Deng, H. Y., and Fan, W. K. [Effect of Janus kinase inhibitor AG490 on invasion and metastasis of human breast cancer cells]. Sichuan Da Xue Xue Bao Yi Xue Ban, 39: 63-65, 83, 2008.

Certificate of Analysis/MSDS is available upon request with lot number

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