IBMX
Catalog #:
IN0120| IN0120-200mg | USD59.0 |
| IN0120-1g | USD240.0 |
Synonyms: 1-Methyl-3-isobutylxanthine, 3-Isobutyl-1-methylxanthine, 3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione
IUPAC Name:
3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Functional Activity:
Phosphodiesterase inhibitor that inhibits both cAMP and cGMP phosphodiesterases. It also sppresses α-adrenoceptor-mediated 5-HT release from neuroendocrine epithelial cells.
Technical Data:
M.Wt: 222.24
Formula: C10H14N4O2
Solubility: Soluble in DMSO
Purity: >99%
Storage: Dessicate at -20°C
CAS No.: 28822-58-4
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References for IBMX
1. Bazwinsky-Wutschke, I., Muhlbauer, E., Wolgast, S., and Peschke, E. Transcripts of calcium/calmodulin-dependent kinases are changed after forskolin- or IBMX-induced insulin secretion due to melatonin treatment of rat insulinoma beta-cells (INS-1). Horm Metab Res, 41: 805-813, 2009.
2. Candia, O. A., Kong, C. W., and Alvarez, L. J. IBMX-elicited inhibition of water permeability in the isolated rabbit conjunctival epithelium. Exp Eye Res, 86: 480-491, 2008.
3. Gautam, S. H., Otsuguro, K., Ito, S., Saito, T., and Habara, Y. T-type Ca2+ channels contribute to IBMX/forskolin- and K(+)-induced Ca(2+) transients in porcine olfactory receptor neurons. Neurosci Res, 57: 129-139, 2007.
4. Barretto, L. S., Caiado Castro, V. S., Garcia, J. M., and Mingoti, G. Z. Role of roscovitine and IBMX on kinetics of nuclear and cytoplasmic maturation of bovine oocytes in vitro. Anim Reprod Sci, 99: 202-207, 2007.
5. Zhang, W. and Delay, R. J. Pulse stimulation with odors or IBMX/forskolin potentiates responses in isolated olfactory neurons. Chem Senses, 31: 197-206, 2006.
6. Koncz, S. and Horvath, E. J. Different action of IBMX, isoproterenol and rutin on orthovanadate-induced nitric oxide release in mouse macrophage cells. Acta Vet Hung, 50: 323-341, 2002.
