SB 431542
Catalog #:
IN0119| IN0119-1mg | USD114.0 |
Synonyms: 4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamide hydrate, 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide hydrate, 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]-benzamide hydrate
IUPAC Name:
4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Functional Activity:
Potent and selective inhibitor of transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase (ALK) receptors. It suppresses TGFβ-induced proliferation of osteosarcoma cells, but stimulates proliferation, differentiation and sheet formation of endothelial cells.
