Spermidine
Catalog #:
IN0118| IN0118-10mg | USD39.0 |
Synonyms: N-(3-Aminopropyl)-1,4-diaminobutane
IUPAC Name:
1,8-Diamino-4-azaoctane
Functional Activity:
Spermidine is a polyamine involved in cellular metabolism. It can be used as an inhibitor of neuronal nitric oxide synthase (nNOS), stimulator of T4 polynucleotide kinase activity, and used for purification of DNA binding proteins.
Technical Data:
M.Wt: 145.25
Formula: C7H19N3
Solubility: Soluble in water
Purity: >98%
Storage: Dessicate at -20°C
CAS No.: 124-20-9
Related Products by Target:
References for Spermidine
1. Kaeberlein, M. Spermidine surprise for a long life. Nat Cell Biol, 11: 1277-1278, 2009.
2. Ohtani, M., Mizuno, I., Kojima, Y., Ishikawa, Y., Sodeno, M., Asakura, Y., Samejima, K., and Oka, T. Spermidine regulates insulin synthesis and cytoplasmic Ca(2+) in mouse beta-TC6 insulinoma cells. Cell Struct Funct, 34: 105-113, 2009.
3. Tanima, D., Imamura, Y., Kawabata, T., and Tsubaki, K. Development of highly sensitive and selective molecules for detection of spermidine and spermine. Org Biomol Chem, 7: 4689-4694, 2009.
4. Murata, T., Miyase, T., and Yoshizaki, F. Meehanines L-W, spermidine alkaloidal glycosides from Meehania urticifolia. J Nat Prod, 72: 1937-1943, 2009.
5. Eisenberg, T., Knauer, H., Schauer, A., Buttner, S., Ruckenstuhl, C., Carmona-Gutierrez, D., Ring, J., Schroeder, S., Magnes, C., Antonacci, L., Fussi, H., Deszcz, L., Hartl, R., Schraml, E., Criollo, A., Megalou, E., Weiskopf, D., Laun, P., Heeren, G., Breitenbach, M., Grubeck-Loebenstein, B., Herker, E., Fahrenkrog, B., Frohlich, K. U., Sinner, F., Tavernarakis, N., Minois, N., Kroemer, G., and Madeo, F. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol, 11: 1305-1314, 2009.
6. Biastoff, S., Reinhardt, N., Reva, V., Brandt, W., and Drager, B. Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding. FEBS Lett, 583: 3367-3374, 2009.
