1-Aminobenzotriazole
Catalog #:
IN0108Shipping advice:
Suitable for Standard Delivery only (2-3 days). International shipping rate please contact us for details
IN0108-100mg | USD142.0 |
Synonyms: 1-Aminobenzotriazole , 1H-Benzotriazol-1-amine, 1-Abtz, 1-Benzotriazolamine

IUPAC Name:
Benzotriazol-1-amine
Functional Activity:
Inhibitor of cytochrome P450 and chloroperoxidase.
Technical Data:
M.Wt: 134.14
Formula: C6H6 N4
Solubility: Soluble in DMSO
Purity: >98%
Storage: Dessicate at RT
CAS No.: 1614-12-6
Related Products by Target:
References for 1-Aminobenzotriazole
1. Hahn, V., Mikolasch, A., Wende, K., Bartrow, H., Lindequist, U., and Schauer, F. Derivatization of the azole 1-aminobenzotriazole using laccase of Pycnoporus cinnabarinus and Myceliophthora thermophila: influence of methanol on the reaction and biological evaluation of the derivatives. Biotechnol Appl Biochem, 56: 43-48.
2. Nan, Y. M., Wu, W. J., Fu, N., Liang, B. L., Wang, R. Q., Li, L. X., Zhao, S. X., Zhao, J. M., and Yu, J. Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice. Scand J Gastroenterol, 44: 1121-1131, 2009.
3. El-Kattan, A. F., Poe, J., Buchholz, L., Thomas, H. V., Brodfuehrer, J., and Clark, A. The use of 1-aminobenzotriazole in differentiating the role of CYP-mediated first pass metabolism and absorption in limiting drug oral bioavailability: a case study. Drug Metab Lett, 2: 120-124, 2008.
4. Linder, C. D., Renaud, N. A., and Hutzler, J. M. Is 1-aminobenzotriazole an appropriate in vitro tool as a nonspecific cytochrome P450 inactivator? Drug Metab Dispos, 37: 10-13, 2009.
5. Strelevitz, T. J., Foti, R. S., and Fisher, M. B. In vivo use of the P450 inactivator 1-aminobenzotriazole in the rat: varied dosing route to elucidate gut and liver contributions to first-pass and systemic clearance. J Pharm Sci, 95: 1334-1341, 2006.
6. Muzeeb, S., Pasha, M. K., Basha, S. J., Mullangi, R., and Srinivas, N. R. Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats. Xenobiotica, 35: 825-838, 2005.