Gadolinium chloride

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Synonyms: Gadolinium (III) chloride, GdCl₃, Gadolinium trichloride

IUPAC Name:

Trichlorogadolinium hydrate

Functional Activity:

Non-selective cation channel (NSCC) blocker

Technical Data:

M.Wt: 263.61

Formula: GdCl₃

Solubility: Soluble to water

Purity: >99%

Storage: Dessicate at RT

CAS No.: 10138-52-0

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References for Gadolinium chloride:

1. Barnhart, J. L., Kuhnert, N., Bakan, D. A., and Berk, R. N. Biodistribution of GdCl3 and Gd-DTPA and their influence on proton magnetic relaxation in rat tissues. Magn Reson Imaging, 5: 221-231, 1987.

2. Ding, H., Shi, G. G., Yu, X., Yu, J. P., and Huang, J. A. Modulation of GdCl3 and Angelica sinensis polysaccharides on differentially expressed genes in liver of hepatic immunological injury mice by cDNA microarray. World J Gastroenterol, 9: 1072-1076, 2003.

3. Giakoustidis, D., Papageorgiou, G., Iliadis, S., Giakoustidis, A., Kostopoulou, E., Kontos, N., Botsoglou, E., Tsantilas, D., Papanikolaou, V., and Takoudas, D. The protective effect of alpha-tocopherol and GdCl3 against hepatic ischemia/reperfusion injury. Surg Today, 36: 450-456, 2006.

4. Henrich, D., Lehnert, M., Herzog, C., Niederlaender, S., Relja, B., Conzelmann, L., and Marzi, I. Differential effects of GdCl3- or MDP treatment on rat liver microcirculation and gene expression in the hepatic non-parenchymal cell fraction in LPS shock. Microcirculation, 15: 427-439, 2008.

5. Jahnke, C., Mehrabi, A., Golling, M., Frankenberg, M. V., Kashfi, A., Nentwich, H., Fonouni, H., Nickkholgh, A., Schemmer, P., Gutt, C. N., Weitz, J., Schmidt, J., Gebhard, M. M., Buchler, M. W., and Kraus, T. Evaluation of microperfusion disturbances in the transplanted liver after Kupffer cell destruction using GdCl3: an experimental porcine study. Transplant Proc, 38: 1588-1595, 2006.

6. Lanza, G. and Minichino, C. Theoretical study of anharmonic and matrix effects on the molecular structure and vibrational frequencies of GdF3 and GdCl3. Chemphyschem, 5: 120-123, 2004.

7. Li, J. Y., Gu, X., Zhang, W. H., Jia, S., and Zhou, Y. GdCl3 abates hepatic ischemia-reperfusion injury by inhibiting apoptosis in rats. Hepatobiliary Pancreat Dis Int, 8: 518-523, 2009.

8. Zissi, G. D. and Yannopoulos, S. N. Dynamic light scattering study of the liquid <--> glass transition for the GdCl3-3AlCl3 glass-forming mixture. Phys Rev E Stat Nonlin Soft Matter Phys, 64: 051504, 2001.

Certificate of Analysis/MSDS is available upon request with lot number