1-Phenylbiguanide

Catalog #:

Shipping advice:

Suitable for Standard Delivery only (2-3 days). International shipping rate please contact us for details

Synonyms: 1-Phenylbiguanide, Phenylbiguanide

IUPAC Name:

None

Functional Activity:

1-phenylbiguanide is a 5-HT₃ receptor agonist.

Technical Data:

M.Wt: 177.21

Formula: C₈H₁₁N₅

Solubility: Soluble moderately in ethanol and in DMSO

Purity: >98%

Storage: Dessicate at RT

CAS No.: 102-02-3

Related Products by Target:

References for 1-Phenylbiguanide :

1. Dutta, A. and Deshpande, S. B. Cardio-respiratory reflexes evoked by phenylbiguanide in rats involve vagal afferents which are not sensitive to capsaicin. Acta Physiol (Oxf), 200: 87-95.

2. Portalone, G. and Colapietro, M. The 1:1 cocrystals of the proton-transfer compound dilituric acid--phenylbiguanide monohydrate. Acta Crystallogr C, 63: o181-184, 2007.

3. de Vries, A., Paton, J. F., Lightman, S. L., and Lowry, C. A. Characterisation of c-Fos expression in the central nervous system of mice following right atrial injections of the 5-HT3 receptor agonist phenylbiguanide. Auton Neurosci, 123: 62-75, 2005.

4. Fu, L. W. and Longhurst, J. C. Reflex pressor response to arterial phenylbiguanide: role of abdominal sympathetic visceral afferents. Am J Physiol, 275: H2025-2035, 1998.

5. Dalpiaz, A., Ferretti, V., Gilli, P., and Bertolasi, V. Stereochemistry of serotonin receptor ligands from crystallographic data. Crystal structures of NAN-190.HBr, 1-phenylbiguanide, MDL 72222 and mianserin.HCl and selectivity criteria towards 5-HT1, 5-HT2, and 5-HT3 receptor subtypes. Acta Crystallogr B, 52 ( Pt 3): 509-518, 1996.

6. Higgins, G. A., Joharchi, N., and Sellers, E. M. Behavioral effects of the 5-hydroxytryptamine3 receptor agonists 1-phenylbiguanide and m-chlorophenylbiguanide in rats. J Pharmacol Exp Ther, 264: 1440-1449, 1993.