CPU-23 hydrochloride
Catalog #:
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Synonyms: (1-(1-[(6-methoxy)-naphth-2-yl])-propyl-2-(1-piperidine)-acetyl- 6,7- dimethoxy-1,2,3,4-tetrahydroisoquinoline
IUPAC Name:
1-(2-(6,7-dimethoxy-1-(1-(6-methoxynaphthalen-2-yl)ethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-2-oxoethyl)piperidin-1-ium chloride
Novel L-type Ca channel blocker (IC50=0.51 μM) with a unique molecular structure
Functional Activity:
Technical Data:
M.Wt: 502.7
Formula: C31H38N2O4.HCl
Solubility: Soluble in DMSO and water
Purity: >98%
Storage: Dessicate at 4°C
CAS No.: 132836-32-9
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References for CPU-23 hydrochloride:
1.Dong, H., et al., Cardiovascular effects of CPU-23, a novel L-type calcium channel blocker with a unique molecular structure. Br. J. Pharmacol. 122:1271, 1997.
2.Dong, H., et al., Calcium antagonistic and antiarrhythmic actions of CPU-23, a substituted tetrahydroisoquinoline. Br. J. Pharmacol. 109:113, 1993.
3.Dong, H., et al., Cardiovascular effects of substituted tetrahydroisoquinolines in rats. Br. J. Pharmacol. 107:262, 1992.