FFA

Catalog #:

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Synonyms: N-(α,α,α-Trifluoro-m-tolyl)anthranilic acid, N-(3-[Trifluoromethyl]phenyl)anthranilic acid, flufenamic acid, FFA

IUPAC Name:

Functional Activity:

Specific TRPC6 activator when concentration is ≤200 μM.

Technical Data:

M.Wt: 281.23

Formula: C₁₄H₁₀F₃ NO₂

Solubility: Soluble in DMSO

Purity: >98%

Storage: Dessicate at 4°C

CAS No.: 530-78-9

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References for FFA:

1.Chow, JY et al., Calcium-sensing receptor modulates extracellular Ca2+ entry via TRPC-encoded receptor-operated channels in human aortic smooth muscle cells. Am. J. Physiol. Cell Physiol. 301:C461, 2011.

2.Foster RR, et al, Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells. Cell Calcium. 45:384, 2009.

3.Inoue, R et al., The transient receptor potential protein homologue TRP6 is the essential component of vascular ?1-adrenoceptor-activated Ca2+-permeable cation channel. Circ Res 88: 325?332, 2001.

Certificate of Analysis/MSDS is available upon request with lot number