Acetazolamide
Catalog #:
IN0078IN0078-100mg | USD59.0 |
Synonyms: 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide

IUPAC Name:
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide
Functional Activity:
Selective carbonic anhydrase (CA) inhibitor
Technical Data:
M.Wt: 222.25
Formula: C4H6 N4O3S2
Solubility: Soluble in 50mg/mL DMSO and 1 M NH4OH
Purity: >99%
Storage: Dessicate at RT
CAS No.: 59-66-5
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References for Acetazolamide:
1. Bin, K. and Shi-Peng, Z. Acetazolamide Inhibits Aquaporin-1 Expression and Colon Cancer Xenograft Tumor Growth. Hepatogastroenterology, 58.
2. Ahlskog, J. K., Dumelin, C. E., Trussel, S., Marlind, J., and Neri, D. In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives. Bioorg Med Chem Lett, 19: 4851-4856, 2009.
3. Lammoglia, J. J. and Mericq, V. Familial tumoral calcinosis caused by a novel FGF23 mutation: response to induction of tubular renal acidosis with acetazolamide and the non-calcium phosphate binder sevelamer. Horm Res, 71: 178-184, 2009.
4. Lyall, D. A. Unexpected control of a patient's refractory epilepsy when treating glaucoma with acetazolamide. Can J Ophthalmol, 43: 377, 2008.
5. Ito, H., Shidahara, M., Inoue, K., Goto, R., Kinomura, S., Taki, Y., Okada, K., Kaneta, T., Sato, K., Sato, T., and Fukuda, H. Effects of tissue heterogeneity on cerebral vascular response to acetazolamide stress measured by an I-123-IMP autoradiographic method with single-photon emission computed tomography. Ann Nucl Med, 19: 251-260, 2005.
6. Longatti, P., Marton, E., and Billeci, D. Acetazolamide and corticosteroid therapy in complicated arachnoid cyst. Childs Nerv Syst, 21: 1061-1064, 2005.