Cimetidine
Catalog #:
IN0074| IN0074-100mg | USD45.0 |
Synonyms: Cimetidine, Tagamet, Cimetag, Acibilin, Cimetum, Tametin, Gastromet
IUPAC Name:
2-cyano- 1-methyl- 3-(2-[(5-methyl- 1H-imidazol- 4-yl)methylthio]ethyl)guanidine
Functional Activity:
Cimetidine is a histamine H2-receptor antagonist that inhibits the production of acid in the stomach. It is largely used in the treatment of heartburn and peptic ulcers. It is also shown to be a potent I1 imidazoline binding site ligand.
Technical Data:
M.Wt: 252.34
Formula: C10H16 N6S
Solubility: Soluble to 50 mM in water and to 100 mM in DMSO
Purity: >99%
Storage: Dessicate at 4°C
CAS No.: 51481-61-9
Related Products by Target:
References for Cimetidine:
1. Kawase, J., Ozawa, S., Kobayashi, K., Imaeda, Y., Umemoto, S., Matsumoto, S., and Ueda, M. Increase in E-selectin expression in umbilical vein endothelial cells by anticancer drugs and inhibition by cimetidine. Oncol Rep, 22: 1293-1297, 2009.
2. Arndt, P. A., Garratty, G., Brasfield, F. M., Vemuri, S. L., and Asuncion, D. J. Immune hemolytic anemia due to cimetidine: the first example of a cimetidine antibody. Transfusion, 50: 302-307.
3. Chihara, Y., Fujimoto, K., Miyake, M., Hiasa, Y., and Hirao, Y. Anti-tumor effect of cimetidine via inhibiting angiogenesis factors in N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse and rat bladder carcinogenesis. Oncol Rep, 22: 23-28, 2009.
4. Stefani, M., Bottino, G., Fontenelle, E., and Azulay, D. R. [Efficacy comparison between cimetidine and zinc sulphate in the treatment of multiple and recalcitrant warts]. An Bras Dermatol, 84: 23-29, 2009.
