Dopamine Hydrochloride
Catalog #:
AG0003| AG0003-100mg | USD90.0 |
Synonyms: Dopamine hydrochloride, Intropin, 3-Hydroxytyramine hydrochloride, Revivan, Dopastat, m-Hydroxytyramine hydrochloride
IUPAC Name:
4-(2-aminoethyl)benzene-1,2-diol hydrochloride
Functional Activity:
Dopamine (sometimes abbreviated DA) is a catecholamine neurotransmitter present in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this substituted phenethylamine functions as a neurotransmitter, activating the five known types of dopamine receptors, D1, D2, D3, D4, and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary.
Technical Data:
M.Wt: 189.64
Formula: C8H11 N O2.HCl
Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
Purity: >98%
Storage: Dessicate at -20°C
CAS No.: 62-31-7
Special Conditions:
This product is a Dangerous Good (UN1544) and carries a $10 dangerous goods packaging fee.
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References for Dopamine:
1. Almeida, L. E., Murray, P. D., Zielke, H. R., Roby, C. D., Kingsbury, T. J., and Krueger, B. K. Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine- and cAMP-induced CREB-dependent gene transcription. J Neurosci, 29: 12702-12710, 2009.
2. Grant, A., Speed, Z., Labelle-Dumais, C., and Flores, C. Post-pubertal emergence of a dopamine phenotype in netrin-1 receptor-deficient mice. Eur J Neurosci, 30: 1318-1328, 2009.
3. Kriks, S. and Studer, L. Protocols for generating ES cell-derived dopamine neurons. Adv Exp Med Biol, 651: 101-111, 2009.
4. Sayyah-Melli, M., Tehrani-Gadim, S., Dastranj-Tabrizi, A., Gatrehsamani, F., Morteza, G., Ouladesahebmadarek, E., Farzadi, L., and Kazemi-Shishvan, M. Comparison of the effect of gonadotropin-releasing hormone agonist and dopamine receptor agonist on uterine myoma growth. Histologic, sonographic, and intra-operative changes. Saudi Med J, 30: 1024-1033, 2009.
5. Bence, M., Kereszturi, E., Mozes, V., Sasvari-Szekely, M., and Keszler, G. Hypoxia-induced transcription of dopamine D3 and D4 receptors in human neuroblastoma and astrocytoma cells. BMC Neurosci, 10: 92, 2009.
