Monensin A Sodium Salt
Catalog #:
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Synomyms: Monensin, Elancoban, Monelan, Monensinum, Monensina, Lilly673140, Monensic acid, Monensin A
IUPAC Name:
4-[2-[5-ethyl-5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-oxan-2-yl]- 3-methyl-oxolan-2-yl]oxolan-2-yl]- 9-hydroxy-2,8-dimethyl-1,6-dioxasp iro[4.5]dec-7-yl]-3-methoxy-2-methyl-pentanoic acid
Functional Activity:
Monensin is a polyether antibiotic isolated from Streptomyces cinnamonensis. It is widely used in animal feeds. It is a Na+ ionophore; blocks glycoprotein secretion; may induce catecholamine secretion from chromaffin cells. Useful in potentiometric and spectroscopic studies of alkali metal ion complexes.
Technical Data:
M.Wt: 692.85
Formula: C36H61 NaO11
Solubility: Soluble in DMSO and ethanol
Purity: >90%
Storage: Dessicate at 4°C
CAS No.: 22373-78-0
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References for Monensin A:
1. Henri, J., Burel, C., Sanders, P., and Laurentie, M. Bioavailability, distribution and depletion of monensin in chickens. J Vet Pharmacol Ther, 32: 451-456, 2009.
2. Pantcheva, I. N., Dorkov, P., Atanasov, V. N., Mitewa, M., Shivachev, B. L., Nikolova, R. P., Mayer-Figge, H., and Sheldrick, W. S. Crystal structure and properties of the copper(II) complex of sodium monensin A. J Inorg Biochem, 103: 1419-1424, 2009.
3. Dubuc, J., Baril, J., and DesCoteaux, L. [The use of monensin premix in dairy cows: simple and essential steps for ensuring its proper use]. Can Vet J, 50: 617-619, 2009.
4. Varga, A., Schober, K. E., Holloman, C. H., Stromberg, P. C., Lakritz, J., and Rings, D. M. Correlation of serum cardiac troponin I and myocardial damage in cattle with monensin toxicosis. J Vet Intern Med, 23: 1108-1116, 2009.
5. Karnati, S. K., Yu, Z., and Firkins, J. L. Investigating unsaturated fat, monensin, or bromoethanesulfonate in continuous cultures retaining ruminal protozoa. II. Interaction of treatment and presence of protozoa on prokaryotic communities. J Dairy Sci, 92: 3861-3873, 2009.
6. Karnati, S. K., Sylvester, J. T., Ribeiro, C. V., Gilligan, L. E., and Firkins, J. L. Investigating unsaturated fat, monensin, or bromoethanesulfonate in continuous cultures retaining ruminal protozoa. I. Fermentation, biohydrogenation, and microbial protein synthesis. J Dairy Sci, 92: 3849-3860, 2009.
