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IN0044-5mg USD89.0

References for CFTR(inh)-172:

1. Kelly, M., Trudel, S., Brouillard, F., Bouillaud, F., Colas, J., Nguyen-Khoa, T., Ollero, M., Edelman, A., and Fritsch, J. Cystic fibrosis transmembrane regulator inhibitors CFTR(inh)-172 and GlyH-101 target mitochondrial functions, independently of chloride channel inhibition. J Pharmacol Exp Ther, 333: 60-69.

2. Caci, E., Caputo, A., Hinzpeter, A., Arous, N., Fanen, P., Sonawane, N., Verkman, A. S., Ravazzolo, R., Zegarra-Moran, O., and Galietta, L. J. Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis. Biochem J, 413: 135-142, 2008.

3. Yang, B., Sonawane, N. D., Zhao, D., Somlo, S., and Verkman, A. S. Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease. J Am Soc Nephrol, 19: 1300-1310, 2008.

Certificate of Analysis/MSDS is available upon request with lot number

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